2016 | Month: | Volume:3 | Issue:2 | Page:80-87

Bacteriological profile and antimicrobial resistance of blood culture isolates among paediatric patients from tertiary care hospital

Bloodstream infection ranges from self limiting infection to life threatening sepsis and requires rapid and aggressive antimicrobial treatment. A total of 928 blood samples were collected from suspected cases from August 2014 to July 2015, they were processed aerobically and antibiogram pattern was studied . Cultures were positive in 252 (27.16%) cases. All the positive cultures were obtained after 48 hours of incubation. Gram negative bacteria were 84(36.20%) of the total isolates and Gram positive were 108 (46.55%), Candida species were isolated in 40(17.24%) of cases. In gram negative isolates, highest resistance was seen for Ticarcillin- Clavulanic acid 22 (39.29%), Cefoperazone –sulbactum 22 (39.29%), Cefuroxime 22 (39.29%), Cefazolin 22 (39.29%) and Amoxicillin- Clavulanic acid 22 (39.29%); in contrast gram positive isolates showed resistance to Ciprofloxacin 40(100%). Blood cultures provide a valuable guide in identifying etiological agent and selecting appropriate antibiotic. This helps to achieve a high level antibiotic activity against the offending bacterial organism.

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